Hi there @thesotman!
Don here from Shopify.
While it is not possible to change the 'myshopify.com' URL a store was set up under you can definitely re-brand your store in order to pursue a different line of business.
You can change your store's name in the settings > general menu and you can buy or connect a new custom domain via the Online store > Domains menu.
As long as you are redirecting all traffic to this new custom domain as your primary domain, then customers visiting your store would only see this URL when browsing your store.
You can also then remove your existing products or get started with adding new ones for your new store.
Do you know what new direction you wanted to take your store in?