Yes, the Orders API will give you all your orders for Online and POS sales channels. You can then filter out POS orders using the "source_name" and "location" fields if you have multiple locations.
The TenderTransaction API is also handy if you just want to check tender amounts (charges/refunds).
TenderTransaction API: https://help.shopify.com/en/api/reference/tendertransaction#index
If you want to see what kind of info these APIs return, you can always access them from the Admin.