I'm not 100% sure about what you mean. Do you mean to have multiple costs for one product? Or do you mean to just make sure your costs are covered based on the difference in shipping prices to different places?
If you could elaborate a little further on what exactly you mean it would greatly be appreciated and hugely helpful to perhaps finding a solution or giving you an answer to what you're looking for.
Looking forward to hearing from you.
All the best, Nick
Each product you sell can only have one price. You can adjust the price if you wish, but it wouldn't be possible to have one product with more than one cost.
Shopify does have a helpful guide about price-setting strategies which could be worth your time looking into and which you can read here. There is one section of the guide which I think is the most relevant to you which I screenshot and you can see it below:
This subject speaks to Product Costing, in general, which perhaps is a future enhancement for Shopify POS but not supported now. Ideally, costing would require the use of Purchase Orders, where item costs are specified. The receipt of goods against a PO should allow the posting of additional non-merchandise costs i.e. inbound freight, duty, etc. These "landed costs" could also be posted during the entry of the invoice for any given receipt.
Shopify would then have to offer the user several inventory costing methods, i.e. Standard, FIFO, LIFO, etc., or at least export the appropriate info to an accounting system via an integration, where the inventory costing is ultimately carried.
There are other scenarios i.e. where some products may carry a specific cost, inherited at time of receipt and invoice (from the vendor) that follows the item throughout its lifecycle. Typically, these products would be serialized. The bottom line is that Shopify POS is not an accounting system. Advanced inventory costing is only found in retail solutions that are built and scaled for larger retailers.