Using GraphQL to update the custom attributes of a specific order line item

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I have to admit that GraphQL is a mystery to me.  I've spent hours trying to figure this out.

Let's say I have order Id: 2812959195213, product id: 4918373154893 and variant id: 33307973320781.  I need to add or update the line item properties for that specific product variant in that specific order.  I believe I need to use a mutation.  Can someone show me the code that would do this?