Possible to set up four pricing tiers and selectively display?

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TIA for the help from this community! We currently have a site for national ecommerce with two pricing tiers, the "compare at" and the actual price. 

Here's the question, we want to set up two local pickup sections on the current site with two pricing: open box and new unopened. These prices would be different from the national ecommerce pricing and we don't want to confuse the two audiences by showing all four prices to the same sku.

Is it possible to set that up with the standard shopify package? if not, how much would it take to get this done?

Thanks again