Do I need to use Remix to work with Shopify App Bridge 4.x?

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I’ve developed a Shopify app using Node.js, and it’s currently under review. As part of the feedback, I’ve been asked to update the Shopify App Bridge version to the latest (4.x).

I wanted to confirm if it’s mandatory to use Remix to work with App Bridge 4.x or if I can continue with my current Node.js setup. Are there any specific steps or considerations I need to be aware of when upgrading to version 4.x in a Node.js environment?

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I’m updating my Shopify app, built with Node.js, to use the latest version of Shopify App Bridge (4.x). However, I encountered an issue where I get the error:

appBridge.subscribe is not a function

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Will App Bridge 4.x work with Shopify’s Node.js boilerplate from the official GitHub repository https://github.com/Shopify/shopify-app-template-node  ?