In short, no it would not be possible. Any domains added to the domains section of your admin will all lead to the same place. However; you could look into using third-party landing pages if you have special event pages.
@Trevor Thank you for the information! My website has an online auction section, Just wanting to make it easy for customers to get to, be great if it could be .com/auctions! I am open to any ideas you have!
It's not currently possible to change the URL structure, so it would need to be /pages/auctions. Including the "auctions" page in your main navigation and/or slideshow on your homepage will likely be the easiest way to direct customers to that specific area. Also ensuring that any ads you run to advertise the auction are using the direct URL vs your store URL.
How are you planning on running on operating an auction in your store?