Yes! You can set the app URL to whathever you want, so you can set your staging URL during the review process, and then when they approve it you can change it for the production URL. I have 2 apps published and till this day i can change the URL if i want to.
Besides that, i’d recommend being mindful of the dynamic URL updating that the shopify CLI uses with Cloudflare/ngrok, personally i have 2 apps created in my account, one for the definitive production URL, and another for the Development version which i will allow to update the URL dynamically.