A general tip would be not to spend too much time focusing on making tweaks for a huge desktop version, as most of your traffic will likely come from mobile.
To achieve the desired outcome, first, make sure you’ve selected the 2-column layout for desktop in the Theme Editor → Product Page.
Then, go into base.css and paste the following code at the bottom of the file:
@media screen and (min-width: 750px) {
.grid {
column-gap: 0px !important;
row-gap: 0px !important;
}
}
This should give you a similar look and feel to what you requested.
A few more things you could do to maximize the effect include using taller product images. Either by cropping them before uploading or by styling them with css in a standing format.
You can also consider increasing your page width in the Theme Editor (under “Layout”).