To publish it on the Shopify App Store, you’ll need to host your app on a stable, production-ready URL—preferably a custom domain—since Shopify requires a consistent endpoint for app validation and merchant use.
If your app URL changes (e.g., moving from Render to a dedicated host), you’ll need to update the App Setup URL in your Shopify Partner Dashboard, and also ensure your embedded app and theme extension code point to the new URL. Using environment variables and a config file can make this switch easier in your codebase.