Hi @ffrht
Thank you for those details and the screenshots. It sounds like you are wanting customers to be able to combine both shipping and in-store pickup items at the checkout. At this time combining both those option at checkout is not supported. If customers wish to order items that are ONLY available for shipping or local pickup along with items that offer the alternate shipping option, they need to place two separate orders to do so.
You can read more about this in our Help Center here: Shopify Help Center - Local Pickup.
I am happy to provide your feedback about this limitation to our developers for further consideration. In the interim, I recommend providing notes to some of your products that they are only available for one shipping option and customers should check them out separately from the rest of their order to take advantage of that.